e., Internet) and serotonin (i.e, SERT). Mephedrone and methylone act as non-selective transporter substrates, thereby stimulating non-exocytotic launch of dopamine, norepinephrine and serotonin. In contrast, MDPV acts to be a potent blocker at DAT and Web, with minor influence at SERT. Administration of mephedrone or methylone to rats raises extra